Description

Cyclobutaneacetonitrile, 3-Cyano-1-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazol-1-Yl]- is a high-value, multi-functional chemical building block that combines a cyclobutane nitrile core with a pyrazole boronic ester pinacol ester (BPin) group. This compound matters for its role as a key intermediate in modern synthetic chemistry, enabling efficient cross-coupling reactions like Suzuki-Miyaura couplings to construct complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling reactions.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides by providing a versatile handle for molecular diversification.
• Material Science: Serves as a precursor for organic electronic materials, such as polymers and small molecules for OLEDs or OFETs.
• Chemical Biology & Medicinal Chemistry: Enables the creation of chemical probes and libraries for drug discovery and target identification.
• Academic & Industrial R&D: A valuable reagent for methodology development and exploring new synthetic pathways in organic chemistry.
• Custom Synthesis: Employed in contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.

Basic Information

Product Name	Cyclobutaneacetonitrile, 3-Cyano-1-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazol-1-Yl]-
CAS No.	1153950-01-6
Molecular Formula	C15H20BN3O2
Molecular Weight	285.15 g/mol
Synonyms	3-Cyano-1-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]cyclobutaneacetonitrile; 1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)-3-cyanocyclobutaneacetonitrile; 3-Cyano-1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)cyclobutaneacetonitrile; Cyclobutaneacetonitrile, 3-cyano-1-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]-; Pyrazole Boronic Ester Pinacol Ester Derivative; BPin-Pyrazole Cyclobutane Nitrile; CAS 1153950-01-6
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for key parameters are available upon request. Our quality management system is designed to meet the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.