Description

1-(2-Fluorobenzyl)-1H-Pyrazole-4-Carboxylic Acid CAS NO 1153368-52-5 is a high-value fluorinated pyrazole derivative, a key building block in modern organic synthesis. Its molecular structure, featuring both a fluorobenzyl group and a carboxylic acid moiety, makes it an essential intermediate for creating complex molecules with targeted biological activity. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Research: Serves as a key scaffold for developing new-generation herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and material science applications, leveraging the fluorine atom's electronic influence.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis Building Block: Provides a versatile handle for further functionalization, enabling the construction of diverse chemical libraries for high-throughput screening.

Basic Information

Product Name	1-(2-Fluorobenzyl)-1H-Pyrazole-4-Carboxylic Acid
CAS No.	1153368-52-5
Molecular Formula	C11H9FN2O2
Molecular Weight	220.20 g/mol
Synonyms	1-[(2-Fluorophenyl)methyl]-1H-pyrazole-4-carboxylic acid; 1-(2-Fluorobenzyl)-1H-pyrazole-4-carboxylic acid; 1H-Pyrazole-4-carboxylic acid, 1-[(2-fluorophenyl)methyl]-; 2-Fluorobenzyl pyrazole-4-carboxylic acid; 4-Carboxy-1-(2-fluorobenzyl)pyrazole; 1153368-52-5; 1-(2-Fluorobenzyl)pyrazole-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 1-(2-Fluorobenzyl)-1H-Pyrazole-4-Carboxylic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research and development specifications. Our commitment to consistent high purity and reliable supply is paramount.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.