Description

trans-(2-Cyclohexylvinyl)Boronic Acid Mida Ester is a high-value, protected boronic acid derivative designed for advanced synthetic applications. This compound is critical for enabling robust, metal-catalyzed cross-coupling reactions, particularly in complex molecule assembly where traditional boronic acids may be unstable. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing novel carbon-carbon bonds with high fidelity.

Application

• Pharmaceutical Intermediate Synthesis: A key building block in Suzuki-Miyaura cross-coupling reactions for creating complex drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides by facilitating the introduction of the cyclohexylvinyl moiety.
• Material Science: Serves as a precursor for synthesizing organic electronic materials and liquid crystals.
• Medicinal Chemistry: Enables parallel synthesis and library development for high-throughput screening due to the stability imparted by the MIDA (N-methyliminodiacetic acid) protecting group.
• Process Chemistry: Offers advantages in multi-step synthesis by allowing sequential cross-coupling reactions without premature deboronation.
• Academic & Industrial R&D: A valuable reagent for methodology development and exploring new catalytic transformations in organic synthesis.

Basic Information

Product Name	trans-(2-Cyclohexylvinyl)Boronic Acid Mida Ester
CAS No.	1152427-99-0
Molecular Formula	C13H20BNO4
Molecular Weight	265.11 g/mol
Synonyms	trans-2-Cyclohexylvinylboronic acid MIDA ester; (E)-2-Cyclohexylvinylboronic acid MIDA ester; N-Methyliminodiacetic acid (E)-2-cyclohexylvinylboronate; B-(trans-2-Cyclohexylvinyl)-N-methyliminodiacetic acid boronate; MIDA Boronate of trans-2-Cyclohexylvinylboronic Acid; (E)-2-Cyclohexylvinyl-1,3,2-dioxaborolane-4,4-diyl)dimethanaminium
EINECS	Contact for details

Quality Control

Our trans-(2-Cyclohexylvinyl)Boronic Acid Mida Ester is manufactured under strict quality control protocols to ensure high chemical purity and batch-to-batch consistency, suitable for demanding research and development applications. Each lot is analyzed by NMR (¹H and ¹³C) and HPLC to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.