Description

trans-2-Phenylvinylboronic Acid Mida Ester is a high-value, protected boronic acid derivative designed for advanced synthetic applications. This compound is crucial for enabling robust and selective cross-coupling reactions, particularly in complex molecule synthesis where traditional boronic acids may be unstable. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing novel carbon-carbon bonds.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a stable, air- and moisture-tolerant coupling partner for the synthesis of biaryl and styrenyl compounds.
• Pharmaceutical Intermediate Synthesis: Used in the construction of complex drug candidates, including kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Employed in the development of novel active ingredients requiring specific phenylvinyl motifs.
• Material Science & OLED Development: Acts as a key building block for creating conjugated organic molecules used in electronic materials.
• Parallel & Combinatorial Chemistry: Ideal for library synthesis due to the enhanced stability provided by the MIDA (N-methyliminodiacetic acid) protecting group.
• Peptide Modification & Bioconjugation: Facilitates the site-specific introduction of aryl groups into biomolecules.

Basic Information

Product Name	trans-2-Phenylvinylboronic Acid Mida Ester
CAS No.	1152427-93-4
Molecular Formula	C₁₃H₁₄BNO₄
Molecular Weight	259.07 g/mol
Synonyms	(E)-2-Phenylethenylboronic Acid MIDA Ester; trans-β-Styrylboronic Acid MIDA Ester; (E)-2-Phenylvinylboronic Acid N-Methyliminodiacetic Acid (MIDA) Ester; MIDA Boronate Ester of trans-2-Phenylvinylboronic Acid; B-(2-Phenylethenyl)-N-methyliminodiacetic acid boronate; 1152427-93-4; (E)-B-(2-Phenylethenyl)-N-methyliminodiacetic acid boronate
EINECS	Contact for details

Quality Control

Our trans-2-Phenylvinylboronic Acid Mida Ester is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for research and development. Each lot undergoes comprehensive analysis, including HPLC for purity and NMR for structural confirmation, to meet the exacting standards required for modern synthetic chemistry. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95% (Anhydrous basis)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.