Description

N,3-Dimethyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzenesulfonamide is a high-purity boronic ester derivative, a critical building block in modern synthetic chemistry. Its value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex molecules. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in constructing biaryl and heterobiaryl scaffolds common in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require specific aromatic coupling.
• Material Science Research: Serves as a functional monomer or building block for creating advanced organic electronic materials, such as those used in OLEDs or organic semiconductors.
• Chemical Biology & Proteomics: Employed in the development of molecular probes and enzyme inhibitors where the boronic acid pinacol ester moiety is utilized for bioconjugation or as a warhead.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis organizations (CSOs) producing bespoke compounds for client R&D programs.

Basic Information

Product Name	N,3-Dimethyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzenesulfonamide
CAS No.	1152274-54-8
Molecular Formula	C14H22BNO4S
Molecular Weight	311.21 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N,3-dimethylbenzenesulfonamide; N,3-Dimethyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide; 4-(Pinacolatoboryl)-N,3-dimethylbenzenesulfonamide; 4-Borono-N,3-dimethylbenzenesulfonamide pinacol ester; Benzenesulfonamide, N,3-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; Boron, [4-[(dimethylamino)sulfonyl]-2-methylphenyl]-, pinacol ester
EINECS	Contact for details

Quality Control

Our N,3-Dimethyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzenesulfonamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.