Description

2-(2-Chloro-3-Methoxyphenyl)-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane is a high-purity boronic ester derivative, a critical building block in modern synthetic chemistry. Its value lies in enabling efficient and selective carbon-carbon bond formation, a cornerstone reaction for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for compounds containing biaryl motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides through palladium-catalyzed coupling reactions.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as polymers and small molecules for OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis and R&D: An indispensable reagent for contract research organizations (CROs) and academic laboratories exploring new synthetic pathways.

Basic Information

Item	Details
Product Name	2-(2-Chloro-3-Methoxyphenyl)-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane
CAS No.	1151564-03-2
Molecular Formula	C13H18BClO3
Molecular Weight	268.54 g/mol
Synonyms	2-(2-Chloro-3-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (2-Chloro-3-methoxyphenyl)boronic acid pinacol ester; 2-Chloro-3-methoxybenzeneboronic acid pinacol ester; 2-Chloro-3-methoxyphenylboronic acid pinacol ester; Pinacol (2-chloro-3-methoxyphenyl)boronate; CAS 1151564-03-2
EINECS	Contact for details

Quality Control

Every batch of 2-(2-Chloro-3-Methoxyphenyl)-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane is manufactured and tested under strict quality management systems to ensure consistency and reliability for your critical applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles as verified by advanced analytical techniques including HPLC, GC, and NMR. Our commitment to quality supports compliance in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic nature, it is recommended to handle the material under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to minimize exposure to moisture. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/GC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.