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Potassium 6-Fluoro-2-Methylpyridine-3-Trifluoroborate CAS NO 1150654-88-8


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CAS No.:1150654-88-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Potassium 6-Fluoro-2-Methylpyridine-3-Trifluoroborate is a high-value organotrifluoroborate salt, a crucial building block in modern synthetic chemistry. Its primary value lies in its exceptional stability and reactivity, making it a superior alternative to traditional boronic acids in cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to introduce the 6-fluoro-2-methylpyridine moiety into complex molecules.

Application

  • Pharmaceutical Intermediate: A key reagent in Suzuki-Miyaura cross-coupling reactions for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of novel drug candidates.
  • Agrochemical Synthesis: Used to construct complex pyridine-based structures found in advanced herbicides, fungicides, and insecticides.
  • Material Science Research: Serves as a precursor for creating functionalized organic materials and ligands for catalysis.
  • Chemical Biology Probes: Enables the labeling and study of biological systems through bioconjugation strategies.
  • Process Chemistry: Valued for its air and moisture stability, facilitating scalable and robust manufacturing processes.

Basic Information

Product Name Potassium 6-Fluoro-2-Methylpyridine-3-Trifluoroborate
CAS No. 1150654-88-8
Molecular Formula C6H5BF4KN
Molecular Weight 209.02 g/mol
Synonyms Potassium (6-Fluoro-2-methylpyridin-3-yl)trifluoroborate; 6-Fluoro-2-methyl-3-pyridinyltrifluoroborate Potassium Salt; 3-Trifluoroboratomethyl-6-fluoropyridine Potassium Salt; Potassium 6-Fluoro-2-methyl-3-pyridyltrifluoroborate; 6-Fluoro-2-methylpyridine-3-trifluoroboronic acid potassium salt; (6-Fluoro-2-methyl-3-pyridinyl)potassium trifluoroborane; Potassium 6-Fluoro-2-methyl-3-pyridyl-BF3
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Quality Control

Our Potassium 6-Fluoro-2-Methylpyridine-3-Trifluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and elemental analysis, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95%
Water Content (KF) ≤ 1.0%
NMR Purity (1H, 19F) ≥ 97%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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