Description

Potassium 1-Trifluoroboratomethylthiomorpholine is a specialized organotrifluoroborate salt, a valuable class of reagents in modern synthetic chemistry. This compound is prized for its stability and utility as a coupling partner in cross-coupling reactions, such as the Suzuki-Miyaura reaction, enabling the efficient construction of complex molecular architectures. It is primarily sought after by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing thiomorpholine and fluorinated motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring boron-based coupling steps.
• Suzuki-Miyaura Cross-Coupling: Serves as a stable, air- and moisture-tolerant organoboron reagent for palladium-catalyzed carbon-carbon bond formation.
• Materials Science Research: Employed in the creation of organic electronic materials, ligands, and complex polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems.
• Process Chemistry & Scale-up: Suitable for optimization and scaling of synthetic routes from laboratory to pilot plant scale.

Basic Information

Product Name	Potassium 1-Trifluoroboratomethylthiomorpholine
CAS No.	1150654-80-0
Molecular Formula	C5H9BF3KNS
Molecular Weight	222.10 g/mol
Synonyms	Potassium (Thiomorpholinomethyl)trifluoroborate; Potassium Thiomorpholinemethyltrifluoroborate; 1-(Trifluoroboratomethyl)thiomorpholine Potassium Salt; Thiomorpholin-1-ylmethyltrifluoroboronic Acid Potassium Salt; (Thiomorpholinomethyl)trifluoroborate Potassium Salt; K-ThioMorphBF3; Potassium Trifluoro(thiomorpholin-1-ylmethyl)borate
EINECS	Contact for details

Quality Control

Our Potassium 1-Trifluoroboratomethylthiomorpholine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 13C, 19F, 11B) and HPLC analysis, to ensure high chemical purity and identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications in GMP and ISO-compliant environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (argon or nitrogen) to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95%
11B NMR Purity	≥95%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.