Description

Potassium 2-Bromothiazole-5-Trifluoroboronate is a high-value organoboron reagent and a key synthetic intermediate in modern cross-coupling chemistry. Its primary value lies in enabling the efficient, selective introduction of the 2-bromothiazole moiety into complex molecular architectures, a critical step in pharmaceutical and agrochemical research. This compound is essential for medicinal chemists and process development scientists working on active ingredients in life sciences.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: As a versatile boronic ester, it is a crucial building block for constructing biaryl and heterobiaryl systems containing the thiazole ring.
• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting infectious diseases, oncology, and central nervous system disorders.
• Agrochemical Synthesis: Serves as a key precursor in developing novel herbicides, fungicides, and insecticides that incorporate the bioactive thiazole heterocycle.
• Material Science Research: Employed in the creation of organic electronic materials, ligands for catalysis, and advanced polymers requiring specific heterocyclic components.
• Chemical Biology & Probe Development: Useful for labeling and modifying biomolecules or creating chemical probes for biological target identification.

Basic Information

Product Name	Potassium 2-Bromothiazole-5-Trifluoroboronate
CAS No.	1150654-69-5
Molecular Formula	C3HBBrF3KN2OS
Molecular Weight	273.93 g/mol
Synonyms	2-Bromothiazol-5-yltrifluoroborate potassium salt; Potassium (2-Bromothiazol-5-yl)trifluoroborate; 2-Bromo-5-thiazolyltrifluoroboronic acid potassium salt; 5-(2-Bromothiazolyl)trifluoroborate potassium; Potassium 2-Bromothiazole-5-yltrifluoroboronate; 2-Bromothiazole-5-boronic acid, trifluoroboronate potassium salt; 2-Bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole, potassium trifluoroborate derivative.
EINECS	Contact for details

Quality Control

Our Potassium 2-Bromothiazole-5-Trifluoroboronate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 13C, 19F, 11B), HPLC, and elemental analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full analytical data are provided for every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) when possible to maintain stability and purity. Keep away from strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
NMR Purity (1H, 19F)	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.