Description

Potassium 6-Bromo-3-Fluoropyridine-2-Trifluoroborate is a high-value organotrifluoroborate salt, a crucial building block in modern synthetic chemistry. Its primary value lies in its exceptional stability and reactivity, making it a superior alternative to traditional boronic acids in cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to construct complex fluorinated and halogenated heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs), particularly those containing fluoropyridine motifs.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides that require specific halogenated pyridine structures.
• Material Science Research: Serves as a building block for creating functionalized organic materials, such as ligands for catalysts or components in organic electronics.
• Chemical Biology Probes: Enables the synthesis of tagged molecules for studying biological processes, leveraging the stability of the trifluoroborate group.
• Custom Synthesis & Contract Manufacturing: Employed by CDMOs for the efficient and scalable production of complex, multi-substituted pyridine derivatives for client projects.

Basic Information

Item	Detail
Product Name	Potassium 6-Bromo-3-Fluoropyridine-2-Trifluoroborate
CAS No.	1150654-62-8
Molecular Formula	C5H2BBrF4KN
Molecular Weight	285.89 g/mol
Synonyms	Potassium (6-Bromo-3-fluoropyridin-2-yl)trifluoroborate; 6-Bromo-3-fluoro-2-pyridyltrifluoroborate Potassium Salt; 2-Pyridyltrifluoroborate, 6-bromo-3-fluoro-, potassium salt; Potassium 6-Bromo-3-fluoropyridine-2-yltrifluoroborate; 6-Bromo-3-fluoropyridine-2-trifluoroborate potassium salt; Potassium 6-Bromo-3-fluoro-2-pyridyltrifluoroboronate
EINECS	Contact for details

Quality Control

Our production of Potassium 6-Bromo-3-Fluoropyridine-2-Trifluoroborate adheres to stringent quality management protocols. Every batch is analyzed using advanced techniques including NMR (1H, 13C, 19F, 11B) and HPLC to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to handle the material under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to minimize exposure to moisture. Recommended storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤1.0%
NMR Purity (19F)	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.