Description

5-Chloro-2-Iodo-1-Methoxy-3-Methylbenzene is a halogenated anisole derivative, a versatile and high-value building block in advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. This compound is primarily sought by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), liquid crystal materials, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides due to its halogenated aromatic structure.
• Liquid Crystal Materials: Serves as a precursor for halogenated liquid crystal compounds used in display technologies.
• Organic Electronic Materials: Intermediate in the production of charge-transport materials and organic semiconductors.
• Cross-Coupling Reactions: Valuable substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.
• Chemical Research & Development: Essential reagent for method development and exploring new synthetic pathways in academic and industrial labs.

Basic Information

Product Name	5-Chloro-2-Iodo-1-Methoxy-3-Methylbenzene
CAS No.	1150617-68-7
Molecular Formula	C8H8ClIO
Molecular Weight	282.51 g/mol
Synonyms	1-Chloro-4-iodo-2-methoxy-5-methylbenzene; 2-Chloro-5-iodo-4-methoxytoluene; 3-Chloro-6-iodo-2-methoxytoluene; 5-Chloro-2-iodo-1-methoxy-3-methyl-benzene; 5-Chloro-2-iodo-3-methylanisole; 2-Iodo-5-chloro-3-methylanisole; 4-Iodo-1-chloro-2-methoxy-5-methylbenzene; Toluene, 2-chloro-5-iodo-4-methoxy-
EINECS	Contact for details

Quality Control

Every batch of 5-Chloro-2-Iodo-1-Methoxy-3-Methylbenzene is produced and tested under strict quality management protocols. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profile as determined by HPLC, GC, NMR, and other relevant spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.