Description

2-(Boc-Amino)-4-Methylphenylboronic Acid,Pinacol is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery and development.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Peptide & Protein Research: Used in the synthesis of modified amino acids and as a handle for bioconjugation strategies.
• Agrochemical Synthesis: Employed in creating advanced crop protection agents and herbicides with specific activity profiles.
• Material Science: Serves as a monomer or functionalization agent in the development of organic electronic materials and polymers.
• Chemical Biology Probes: Facilitates the creation of tagged molecules for studying biological pathways and target engagement.
• Academic & Industrial R&D: A versatile reagent for methodological development and exploring new synthetic routes in laboratory settings.

Basic Information

Product Name	2-(Boc-Amino)-4-Methylphenylboronic Acid,Pinacol
CAS No.	1150561-75-3
Molecular Formula	C₁₈H₂₈BNO₄
Molecular Weight	333.23 g/mol
Synonyms	2-((tert-Butoxycarbonyl)amino)-4-methylbenzeneboronic acid pinacol ester; 2-(Boc-amino)-4-methylbenzeneboronic acid pinacol ester; 2-(N-Boc-amino)-4-methylphenylboronic acid pinacol ester; 2-(tert-Butoxycarbonylamino)-4-methylphenylboronic acid pinacol ester; 2-(Boc-NH)-4-Me-PhBpin; (2-((tert-Butoxycarbonyl)amino)-4-methylphenyl)boronic acid pinacol ester; Boc-2-Amino-4-methylphenyl-Bpin
EINECS	Contact for details

Quality Control

Our 2-(Boc-Amino)-4-Methylphenylboronic Acid,Pinacol is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding synthetic applications. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere. This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.