Description

3-Amino-2-Chloropyridine-6-Boronic Acid, Pinacol Ester is a high-value, multi-functional boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone technology for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Building block for organic electronic materials, including organic light-emitting diodes (OLEDs) and conductive polymers.
• Chemical Biology & Proteomics: Employed in the development of molecular probes and bioconjugation reagents for target identification and validation.
• Ligand Synthesis: Precursor for creating sophisticated ligands used in catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Item	Details
Product Name	3-Amino-2-Chloropyridine-6-Boronic Acid, Pinacol Ester
CAS No.	1150561-74-2
Molecular Formula	C11H16BClN2O2
Molecular Weight	254.52 g/mol
Synonyms	2-Chloro-3-aminopyridine-6-boronic acid pinacol ester; 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-chloropyridin-3-amine; (2-Chloro-3-aminopyridin-6-yl)boronic acid pinacol ester; 3-Amino-2-chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-Chloro-3-pyridinamine-6-boronic acid pinacol ester; 1150561-74-2; 3-Amino-2-chloro-6-pyridineboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 3-Amino-2-Chloropyridine-6-Boronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high purity and structural integrity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.