Description

2-Piperazinylpyridine-3-Boronic Acid, Pinacol Ester is a high-value, functionalized boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and advanced materials. The CAS number for this product is 1150561-73-1.

Application

This versatile boronic ester is primarily employed as a key synthetic intermediate. Its applications include:

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing complex heterocyclic systems.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides through structure-activity relationship (SAR) studies.
• Material Science: Facilitates the creation of novel organic electronic materials, ligands for catalysis, and functional polymers via cross-coupling reactions.
• Chemical Biology & Medicinal Chemistry: Enables the synthesis of probe molecules and library compounds for drug discovery and target identification.
• Catalyst & Ligand Development: Serves as a precursor for synthesizing specialized ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses serving the life sciences sector.

Basic Information

Item	Detail
Product Name	2-Piperazinylpyridine-3-Boronic Acid, Pinacol Ester
CAS No.	1150561-73-1
Molecular Formula	C15H24BN3O2
Molecular Weight	289.19 g/mol
Synonyms	3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(piperazin-1-yl)pyridine; 2-(Piperazin-1-yl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-Piperazin-1-ylpyridine-3-boronic acid pinacol ester; Pyridine-3-boronic acid, 2-(1-piperazinyl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 2-Piperazinylpyridine-3-Boronic Acid, Pinacol Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC for purity assessment and NMR for structural confirmation, to ensure consistency and reliability for your critical synthetic steps. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key specifications such as purity, identity, and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95% (Area %)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.