Description

2-Morpholinopyridine-3-Boronic Acid, Pinacol Ester is a high-value, organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional materials. The CAS number for this compound is provided in the table below.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic programs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring complex aryl-aryl bond formations.
• Material Science Research: Employed in the creation of organic electronic materials, such as polymers for OLEDs and OFETs, where precise molecular architecture is crucial.
• Chemical Biology & Probe Development: Serves as a versatile handle for bioconjugation and the synthesis of molecular probes for target identification and validation.
• Library Synthesis for Drug Discovery: Facilitates the rapid generation of diverse compound libraries via high-throughput parallel synthesis for screening campaigns.
• Catalyst & Ligand Development: Acts as a precursor for synthesizing novel ligands and catalysts used in asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	2-Morpholinopyridine-3-Boronic Acid, Pinacol Ester
CAS No.	1150561-72-0
Molecular Formula	C15H21BN2O3
Molecular Weight	288.15 g/mol
Synonyms	2-(Morpholin-4-yl)pyridine-3-boronic acid pinacol ester; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(morpholin-4-yl)pyridine; 2-Morpholino-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-(4-Morpholinyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-Morpholin-3-pyridineboronic acid pinacol ester; Boronic acid, B-[2-(4-morpholinyl)-3-pyridinyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 2-Morpholinopyridine-3-Boronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR (1H, 13C, 11B) for structural confirmation, to ensure compliance with exacting R&D and process chemistry standards. Comprehensive Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry place. This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent hydrolysis of the boronic ester. Allow the sealed container to reach ambient temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.