Description

3-Carboxy-5-Methylphenylboronic Acid, Pinacol Ester is a high-purity, synthetically valuable boronic ester derivative. This compound serves as a crucial protected intermediate in modern organic synthesis, particularly in cross-coupling reactions. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality building blocks for complex molecule assembly.

Application

• Pharmaceutical Intermediate: A key protected building block in the synthesis of active pharmaceutical ingredients (APIs) via Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific aryl-boronate motifs.
• Material Science Research: Employed in the creation of organic electronic materials, such as polymers for OLEDs and organic photovoltaics.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the development of molecular probes and sensors.
• Catalyst & Ligand Development: Serves as a precursor for synthesizing novel ligands and organometallic catalysts.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring functionalized aryl boronate esters.

Basic Information

Product Name	3-Carboxy-5-Methylphenylboronic Acid, Pinacol Ester
CAS No.	1150561-67-3
Molecular Formula	C15H21BO4
Molecular Weight	276.14 g/mol
Synonyms	(3-Carboxy-5-methylphenyl)boronic acid pinacol ester; 5-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-methylbenzoic acid; 3-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid; Pinacol (3-Carboxy-5-methylphenyl)boronate; Boronic acid, B-(3-carboxy-5-methylphenyl)-, 1,1-dimethylethyl ester (9CI)
EINECS	Contact for details

Quality Control

Our 3-Carboxy-5-Methylphenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.