Description

4,4,5,5-Tetramethyl-2-(2-Methyl-5-(Trifluoromethylsulfonyl)Phenyl)-1,3,2-Dioxaborolane is a high-purity, advanced boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation, particularly in the synthesis of complex, functionalized molecules for high-value applications. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing trifluoromethylsulfonyl and aryl-boronate motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Suzuki-Miyaura Cross-Coupling: A versatile reagent for palladium-catalyzed coupling reactions to form biaryl and heterobiaryl structures.
• Chemical Biology & Probe Development: Utilized in the design and synthesis of molecular probes and inhibitors for biochemical research.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing specialized ligands and organometallic catalysts.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-(2-Methyl-5-(Trifluoromethylsulfonyl)Phenyl)-1,3,2-Dioxaborolane
CAS No.	1150271-69-4
Molecular Formula	C14H18BF3O4S
Molecular Weight	350.16 g/mol
Synonyms	2-(2-Methyl-5-(trifluoromethylsulfonyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (2-Methyl-5-(trifluoromethylsulfonyl)phenyl)boronic acid pinacol ester; 2-Methyl-5-(trifluoromethylsulfonyl)benzeneboronic acid pinacol ester; 5-(Pinacolatoboran)-2-methyl-1-(trifluoromethylsulfonyl)benzene; CAS 1150271-69-4; Aryltrifluoromethylsulfonyl boronate ester
EINECS	Contact for details

Quality Control

Our 4,4,5,5-Tetramethyl-2-(2-Methyl-5-(Trifluoromethylsulfonyl)Phenyl)-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to handle the material under an inert atmosphere (e.g., nitrogen or argon) and store the container in a desiccator to prevent moisture absorption. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.