Description

3-(Ethoxycarbonyl)-5-Methylphenylboronic Acid, Pinacol Ester is a high-purity, synthetically valuable boronic ester derivative. This compound serves as a critical protected intermediate in modern cross-coupling reactions, enabling the precise construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for the development of active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in medicinal chemistry programs targeting complex biaryl structures.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the boronic ester group facilitates efficient carbon-carbon bond formation.
• Material Science Research: Employed in the creation of organic electronic materials, such as polymers and small molecules for OLEDs or organic photovoltaics, due to its functional handle for polymerization or derivatization.
• Chemical Biology Probes: Acts as a precursor for synthesizing tagged molecules or bioconjugates used in proteomics and diagnostic assay development.
• Process Chemistry & Scale-up: The pinacol ester protection enhances stability, making this compound suitable for multi-step synthesis and potential commercial-scale manufacturing processes.
• Academic & Contract Research: Essential reagent in university and CRO laboratories for methodological development in synthetic organic chemistry and catalysis studies.

Basic Information

Product Name	3-(Ethoxycarbonyl)-5-Methylphenylboronic Acid, Pinacol Ester
CAS No.	1150271-63-8
Molecular Formula	C17H25BO4
Molecular Weight	304.19 g/mol
Synonyms	5-Methyl-3-(ethoxycarbonyl)phenylboronic acid pinacol ester; (3-(Ethoxycarbonyl)-5-methylphenyl)boronic acid pinacol ester; Pinacol [3-(ethoxycarbonyl)-5-methylphenyl]boronate; 3-Carbethoxy-5-methylbenzeneboronic acid pinacol ester; B-[3-(Ethoxycarbonyl)-5-methylphenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Ethyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-methylbenzoate; CAS 1150271-63-8
EINECS	Contact for details

Quality Control

Our 3-(Ethoxycarbonyl)-5-Methylphenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to maintain product integrity and prevent hydrolysis.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0% (Area %)
Purity (GC)	≥96.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.