Description

5-(Ethoxycarbonyl)Thiophene-2-Boronic Acid, Pinacol Ester is a high-purity organoboron building block essential for modern synthetic chemistry. This compound is a key reagent in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex thiophene-based molecular architectures. It is primarily utilized by pharmaceutical, agrochemical, and advanced materials researchers for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing active pharmaceutical ingredients (APIs), particularly those containing functionalized thiophene cores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides with tailored properties.
• Material Science: Enables the creation of conjugated polymers and organic electronic materials for applications in OLEDs, organic photovoltaics (OPVs), and sensors.
• Chemical Research: Serves as a versatile reagent in academic and industrial R&D for palladium-catalyzed cross-coupling reactions to form new carbon-carbon bonds.
• Ligand & Catalyst Development: Used as a precursor for synthesizing specialized ligands and catalysts in homogeneous catalysis.

Basic Information

Product Name	5-(Ethoxycarbonyl)Thiophene-2-Boronic Acid, Pinacol Ester
CAS No.	1150271-60-5
Molecular Formula	C13H19BO4S
Molecular Weight	282.16 g/mol
Synonyms	5-(Ethoxycarbonyl)thiophen-2-ylboronic acid pinacol ester; 2-(5-Ethoxycarbonylthiophen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Ethyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene-2-carboxylate; Thiophene-2-boronic acid, 5-(ethoxycarbonyl)-, pinacol ester; Pinacol 5-(ethoxycarbonyl)thiophene-2-boronate; 5-Carbethoxy-2-thienylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 5-(Ethoxycarbonyl)Thiophene-2-Boronic Acid, Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, typically ≥95% (by HPLC). Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity (NMR, IR), and impurity profiles. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C (refrigerated) or as specified on the label. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon/nitrogen) when possible to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.