Description

5-Acetyl-2,3-Methylenedioxophenylboronic Acid,Pinacol is a specialized organoboron compound, specifically a pinacol-protected boronic acid ester. This chemical serves as a crucial advanced synthetic intermediate in modern organic synthesis, particularly for cross-coupling reactions. It is primarily utilized by pharmaceutical R&D and fine chemical manufacturers for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing complex aryl or heteroaryl structures.
• Suzuki-Miyaura Cross-Coupling: The protected boronic acid functionality makes it a stable and effective reagent for palladium-catalyzed carbon-carbon bond formation, a cornerstone reaction in medicinal chemistry.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that require specific aryl-acetyl motifs.
• Material Science Precursor: Employed in the synthesis of organic electronic materials, such as ligands for OLEDs or molecular sensors, where the acetyl and dioxole groups modify electronic properties.
• Academic & Contract Research: Serves as a valuable reagent for methodology development and the synthesis of novel chemical entities in research laboratories.

Basic Information

Product Name	5-Acetyl-2,3-Methylenedioxophenylboronic Acid,Pinacol
CAS No.	1150271-59-2
Molecular Formula	C15H19BO5
Molecular Weight	290.12 g/mol
Synonyms	5-Acetyl-1,3-benzodioxol-5-ylboronic acid pinacol ester; 2-(5-Acetyl-2,3-dihydro-1,4-benzodioxin-6-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 5-Acetyl-2,3-methylenedioxyphenylboronic acid pinacol ester; (5-Acetyl-1,3-benzodioxol-5-yl)boronic acid pinacol ester; 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-acetyl-1,3-benzodioxole; Pinacol (5-Acetyl-1,3-benzodioxol-5-yl)boronate
EINECS	Contact for details

Quality Control

Our production of 5-Acetyl-2,3-Methylenedioxophenylboronic Acid,Pinacol adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and MS analysis. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.