Description

2-Methoxy-n-(2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzyl)Ethanamine is a specialized boronic ester derivative, a key building block in modern synthetic organic chemistry. Its value lies in its dual functionality, combining a protected boronic acid group with a methoxy-amine moiety, enabling precise cross-coupling and functionalization reactions. This compound is essential for researchers and manufacturers in pharmaceutical development, agrochemical synthesis, and advanced material science who require high-purity intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders and oncology.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic ester reagent for forming carbon-carbon bonds, a fundamental step in creating complex organic molecules.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific aromatic amine-boronate structures.
• Ligand and Catalyst Development: Employed in the design and preparation of novel ligands for transition metal catalysts used in asymmetric synthesis.
• Material Science Research: A building block for creating organic electronic materials, such as those used in OLEDs and semiconductors, where precise molecular engineering is required.
• Chemical Biology & Proteomics: Utilized in the development of molecular probes and activity-based protein profiling (ABPP) agents due to its reactive handles.

Basic Information

Product Name	2-Methoxy-n-(2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzyl)Ethanamine
CAS No.	1150271-51-4
Molecular Formula	C16H26BNO3
Molecular Weight	291.20 g/mol
Synonyms	2-Methoxy-N-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl]ethanamine; 2-(2-Methoxyethylamino)methylphenylboronic acid pinacol ester; N-(2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)-2-methoxyethanamine; 2-Methoxy-N-((2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methyl)ethanamine; (2-((2-Methoxyethylamino)methyl)phenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-Methoxy-n-(2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzyl)Ethanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.