Description

7-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Indolin-2-One is a high-purity, advanced pharmaceutical intermediate and versatile organic building block. This compound is critical for enabling efficient cross-coupling reactions, particularly in the synthesis of complex, nitrogen-containing heterocycles. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition and other biological pathways.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a crucial boronic ester reagent for constructing carbon-carbon bonds between aromatic and heteroaromatic systems.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require complex indolinone-based structures.
• Material Science: Employed in the research and synthesis of organic electronic materials and functional polymers.
• Academic & R&D Laboratories: A valuable tool for synthetic organic chemists exploring new methodologies and complex molecule construction.
• Fine Chemical Synthesis: Building block for creating specialty chemicals, dyes, and pigments with specific optical or electronic properties.

Basic Information

Product Name	7-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Indolin-2-One
CAS No.	1150271-45-6
Molecular Formula	C14H18BNO3
Molecular Weight	259.11 g/mol
Synonyms	7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-dihydro-2H-indol-2-one; 7-(Tetramethyl-1,3,2-dioxaborolan-2-yl)indolin-2-one; 2-Oxo-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indoline; 7-BPin-indolin-2-one; 7-(Pinacolboryl)indolin-2-one; 2-Indolinone, 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 1150271-45-6
EINECS	Contact for details

Quality Control

Our production of 7-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Indolin-2-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and MS to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.