Description

2-Bromo-n-(4-Methoxybenzyl)-4-Nitroaniline CAS NO 1150271-16-1 is a specialized aromatic amine derivative characterized by its bromo, nitro, and methoxybenzyl functional groups. This compound serves as a crucial advanced pharmaceutical intermediate and a versatile building block in organic synthesis. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders or as kinase inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or plant growth regulators where its specific substitution pattern is beneficial.
• Material Science: Serves as a monomer or precursor for functional polymers, dyes, and pigments requiring nitroaniline-based chromophores.
• Organic Synthesis Reagent: Employed in palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination) and nucleophilic substitution reactions due to the reactive bromo and nitro groups.
• Chemical Research: A valuable substrate for methodological studies in synthetic organic chemistry and for creating compound libraries in drug discovery programs.

Basic Information

Product Name	2-Bromo-n-(4-Methoxybenzyl)-4-Nitroaniline
CAS No.	1150271-16-1
Molecular Formula	C14H13BrN2O3
Molecular Weight	337.17 g/mol
Synonyms	2-Bromo-N-[(4-methoxyphenyl)methyl]-4-nitroaniline; 4-Nitro-2-bromo-N-(4-methoxybenzyl)aniline; Benzenamine, 2-bromo-N-[(4-methoxyphenyl)methyl]-4-nitro-; 2-Bromo-4-nitro-N-(4-methoxybenzyl)aniline; N-(4-Methoxybenzyl)-2-bromo-4-nitroaniline; 1150271-16-1; 2-Br-N-(4-MeOBn)-4-NO2-Aniline
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-n-(4-Methoxybenzyl)-4-Nitroaniline is produced and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and MS is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.