Description

5-Chloro-6-Ethoxypyridine-3-Boronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its primary value lies in its role as a key reagent in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries, where it is used to develop new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging its pyridine core for bioactivity.
• Material Science Research: Serves as a monomer or precursor for creating organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and labeled compounds for biochemical assays and diagnostic research.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	5-Chloro-6-Ethoxypyridine-3-Boronic Acid
CAS No.	1150114-68-3
Molecular Formula	C7H9BClNO3
Molecular Weight	201.41 g/mol
Synonyms	(5-Chloro-6-ethoxypyridin-3-yl)boronic acid; 5-Chloro-6-ethoxy-3-pyridineboronic acid; 3-Borono-5-chloro-6-ethoxypyridine; 5-Chloro-6-ethoxy-3-pyridinylboronic acid; Boronic acid, B-(5-chloro-6-ethoxy-3-pyridinyl)-; 1150114-68-3; 5-Chloro-6-ethoxypyridine-3-boronic acid pinacol ester (protected form)
EINECS	Contact for details

Quality Control

Every batch of 5-Chloro-6-Ethoxypyridine-3-Boronic Acid is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as purity (by HPLC/NMR), identity confirmation, and impurity profiles. Our quality commitment supports compliance in cGMP and ISO 9001 environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under inert atmosphere (argon/nitrogen) for long-term stability and to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.