Description

3-(4-Bromophenyl)-1,1,1-Trifluoro-2-Propanol is a high-value fluorinated organic building block characterized by its bromophenyl and trifluoromethyl alcohol functional groups. This compound is essential for the synthesis of advanced pharmaceutical intermediates and agrochemicals, where its unique structure imparts desirable metabolic stability and lipophilicity. It is primarily sought by R&D chemists and process development scientists in the life sciences and specialty chemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in candidates targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of novel herbicides and pesticides, where the trifluoromethyl group enhances biological activity.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for advanced display technologies.
• Organic Light-Emitting Diodes (OLEDs): Employed in the synthesis of electron-transport or host materials for OLED devices.
• Cross-Coupling Reactions: The bromophenyl moiety makes it a valuable substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create biaryl structures.
• Material Science Research: Investigated as a monomer or modifier for introducing fluorine into polymers to alter surface properties and stability.

Basic Information

Product Name	3-(4-Bromophenyl)-1,1,1-Trifluoro-2-Propanol
CAS No.	1148050-30-9
Molecular Formula	C9H6BrF3O
Molecular Weight	267.04 g/mol
Synonyms	1-(4-Bromophenyl)-3,3,3-trifluoro-2-propanol; 4-Bromo-α-(trifluoromethyl)benzenemethanol; 3,3,3-Trifluoro-1-(4-bromophenyl)-2-propanol; 2-Propanol, 3-(4-bromophenyl)-1,1,1-trifluoro-; 1-(4-Bromophenyl)-3,3,3-trifluoropropan-2-ol; α-(Trifluoromethyl)-4-bromobenzyl alcohol; 4-Bromo-α-(trifluoromethyl)benzyl alcohol
EINECS	Contact for details

Quality Control

Our 3-(4-Bromophenyl)-1,1,1-Trifluoro-2-Propanol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.