Description

5-(4-Fluoro-Phenyl)-Pyrazine-2,3-Dicarboxylic Acid is a high-value, multi-functional heterocyclic building block characterized by its pyrazine core and dicarboxylic acid functionality. This compound is essential for advanced organic synthesis, serving as a critical precursor for the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of potential drug candidates, particularly in areas like kinase inhibitors, antiviral agents, and central nervous system (CNS) therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its fluorinated aromatic and heterocyclic structure for bioactivity.
• Ligand & Chelating Agent Precursor: The dicarboxylic acid groups make it a suitable starting material for synthesizing polydentate ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers, dyes, and organic electronic materials.
• Academic & Contract Research: Employed in medicinal chemistry programs and process development for structure-activity relationship (SAR) studies and route scouting.

Basic Information

Product Name	5-(4-Fluoro-Phenyl)-Pyrazine-2,3-Dicarboxylic Acid
CAS No.	1148027-08-0
Molecular Formula	C₁₂H₇FN₂O₄
Molecular Weight	262.20 g/mol
Synonyms	5-(4-Fluorophenyl)pyrazine-2,3-dicarboxylic acid; 2,3-Pyrazinedicarboxylic acid, 5-(4-fluorophenyl)-; 5-(p-Fluorophenyl)pyrazine-2,3-dicarboxylic acid; 4-Fluoro-5-phenylpyrazine-2,3-dicarboxylic acid; 5-(4-Fluorophenyl)-2,3-pyrazinedicarboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 5-(4-Fluoro-Phenyl)-Pyrazine-2,3-Dicarboxylic Acid is manufactured under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing identity, purity (typically ≥95% by HPLC), and impurity profiles is supplied with each shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.