Description

Bromo-Peg3-Phosphonic Acid is a bifunctional organic compound that serves as a versatile building block in advanced chemical synthesis. Its unique structure, featuring a reactive bromine terminus and a phosphonic acid group linked by a triethylene glycol spacer, enables precise conjugation and surface modification. This product is essential for researchers and manufacturers in the pharmaceutical, bioconjugation, and materials science sectors who require reliable, high-purity intermediates for developing targeted therapies and functionalized surfaces.

Application

• Bioconjugation Reagent: Used to functionalize proteins, peptides, and antibodies for drug delivery systems and diagnostic assays.
• Pharmaceutical Intermediate: Serves as a key synthon in the development of prodrugs and targeted small molecule therapeutics.
• Surface Modification Agent: Enables the covalent attachment of biomolecules or polymers to metal oxide surfaces (e.g., titanium, silica) for biosensor and implant coating applications.
• Linker for Solid-Phase Synthesis: Employed in peptide and oligonucleotide synthesis to introduce phosphonate groups or as a cleavable spacer.
• Polymer Functionalization: Used to incorporate phosphonic acid anchoring groups into polymers, enhancing adhesion to inorganic substrates.
• Material Science Research: Acts as a precursor for self-assembled monolayers (SAMs) and hybrid organic-inorganic materials.

Basic Information

Product Name	Bromo-Peg3-Phosphonic Acid
CAS No.	1148026-99-6
Molecular Formula	C9H20BrO6P
Molecular Weight	335.13 g/mol
Synonyms	3-(2-(2-(2-Bromoethoxy)ethoxy)ethoxy)propylphosphonic acid; (3-(2-(2-(2-Bromoethoxy)ethoxy)ethoxy)propyl)phosphonic acid; Br-PEG3-phosphonic acid; Bromo(triethylene glycol)propylphosphonic acid; 2-Bromoethyl-[2-[2-(3-phosphonopropoxy)ethoxy]ethyl] ether; Bromo-PEG3-C3-phosphonate
EINECS	Contact for details

Quality Control

Our Bromo-Peg3-Phosphonic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with stringent specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This compound is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere to maintain stability and purity. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.