Description

(2-Fluoro-Phenyl)-(3-Hydroxy-Piperidin-1-Yl)-Methanone is a high-purity fluorinated piperidine derivative with a molecular formula of C12H14FNO2 and a molecular weight of 223.25. This compound serves as a critical pharmaceutical intermediate and research chemical for the development of novel bioactive molecules. It is essential for R&D and production teams in the pharmaceutical, agrochemical, and fine chemical synthesis sectors seeking to incorporate its unique fluorinated aromatic and hydroxypiperidine motifs.

Application

This fluorinated ketone intermediate is utilized in advanced synthetic chemistry across several key industries:

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, and metabolic diseases.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging the fluorine atom for enhanced biological activity and stability.
• Chemical Biology & Proteomics: Serves as a versatile scaffold or linker in the design of molecular probes and enzyme inhibitors for biochemical research.
• Material Science: Potential precursor for specialty polymers or liquid crystals where the fluorophenyl group imparts specific electronic or physical properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development in organic synthesis and medicinal chemistry projects.

Basic Information

Product Name	(2-Fluoro-Phenyl)-(3-Hydroxy-Piperidin-1-Yl)-Methanone
CAS No.	1146080-21-8
Molecular Formula	C12H14FNO2
Molecular Weight	223.25 g/mol
Synonyms	1-(2-Fluorobenzoyl)-3-hydroxypiperidine; 3-Hydroxy-1-(2-fluorobenzoyl)piperidine; (2-Fluorophenyl)(3-hydroxypiperidin-1-yl)methanone; 2-Fluoro-N-(3-hydroxypiperidin-1-yl)benzamide; Methanone, (2-fluorophenyl)(3-hydroxy-1-piperidinyl)-; 1146080-21-8; AKOS025147065
EINECS	Contact for details

Quality Control

Our (2-Fluoro-Phenyl)-(3-Hydroxy-Piperidin-1-Yl)-Methanone is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure the specified 98+% purity and identity. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.