Description

(2,2,6,6-Tetramethyl-3,6-Dihydro-2H-Pyran-4-Yl)Boronic Acid, Pinacol Ester is a high-purity, advanced boronic ester building block essential for modern synthetic chemistry. This compound matters because it provides a protected, air-stable boronic acid derivative that is crucial for Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. Pharmaceutical, agrochemical, and advanced materials researchers need this reagent for the efficient and reliable synthesis of novel drug candidates, functional polymers, and organic electronic materials.

Application

• Pharmaceutical Intermediate Synthesis: Key building block for constructing complex heterocyclic scaffolds and biaryl structures in active pharmaceutical ingredient (API) development.
• Agrochemical Research: Used in the creation of novel herbicides, fungicides, and insecticides requiring specific sterically hindered boronic acid components.
• Material Science & OLED Development: Enables the synthesis of novel organic semiconductors, light-emitting materials, and charge-transport layers for electronic devices.
• Ligand & Catalyst Design: Serves as a precursor for sophisticated chiral and achiral ligands used in asymmetric catalysis and transition metal complexes.
• Polymer Chemistry: Incorporated into specialty polymers to modify thermal stability, optical properties, or introduce functional handles for further modification.
• Chemical Biology & Probe Development: Utilized in the synthesis of molecular probes and bioconjugates for studying biological processes.

Basic Information

Product Name	(2,2,6,6-Tetramethyl-3,6-Dihydro-2H-Pyran-4-Yl)Boronic Acid, Pinacol Ester
CAS No.	1142363-56-1
Molecular Formula	C15H27BO3
Molecular Weight	266.19 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-2H-pyran, 2,2,6,6-Tetramethyl substituted; 2-(3,6-Dihydro-2H-pyran-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-2H-pyran; 2-(3,6-Dihydro-2,2,6,6-tetramethyl-2H-pyran-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; DHP-BPin; Tetramethyl DHP Boronic Ester
EINECS	Contact for details

Quality Control

Our (2,2,6,6-Tetramethyl-3,6-Dihydro-2H-Pyran-4-Yl)Boronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at 2-8°C for long-term stability. This material is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.