Description

3-(Chloromethyl)-5-Isobutylisoxazole (Saltdata: Free) is a high-purity, versatile heterocyclic building block featuring a reactive chloromethyl group. This compound is crucial for the synthesis of complex molecules, particularly in pharmaceutical research and agrochemical development, where its isoxazole core serves as a key pharmacophore. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the isoxazole moiety.
• Chemical Biology Probe Development: Serves as a precursor for creating molecular probes and labeled compounds used in biochemical and pharmacological research.
• Material Science Research: Potential monomer or cross-linking agent in the development of specialty polymers with unique thermal or chemical properties.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing client-specific advanced intermediates.

Basic Information

Product Name	3-(Chloromethyl)-5-Isobutylisoxazole (Saltdata: Free)
CAS No.	1142210-99-8
Molecular Formula	C8H12ClNO
Molecular Weight	173.64 g/mol
Synonyms	5-Isobutyl-3-(chloromethyl)isoxazole; 3-(Chloromethyl)-5-(2-methylpropyl)-1,2-oxazole; 3-Chloromethyl-5-isobutylisoxazole; 1142210-99-8; 3-(Chloromethyl)-5-isobutyl-1,2-oxazole; 5-(2-Methylpropyl)-3-(chloromethyl)isoxazole
EINECS	Contact for details

Quality Control

Our 3-(Chloromethyl)-5-Isobutylisoxazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to the reactive chloromethyl group, it should be stored separately from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.