Description

1-(1,2-Dihydroxyethyl)-1H-Indole-3-Carbaldehyde is a specialized indole derivative, a versatile building block in advanced organic synthesis. This compound matters for its role as a key chiral intermediate in the development of complex molecules, particularly in the pharmaceutical sector. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for synthesizing novel active ingredients and exploring new chemical entities.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its indole core for biological activity.
• Fine Chemical Synthesis: Serves as a versatile building block for creating specialty chemicals, dyes, and advanced materials.
• Academic & R&D: Employed in university and institutional laboratories for methodological studies in organic chemistry and heterocyclic compound research.
• Bioconjugate Chemistry: The aldehyde and diol functional groups make it suitable for conjugation reactions in probe and linker molecule development.

Basic Information

Product Name	1-(1,2-Dihydroxyethyl)-1H-Indole-3-Carbaldehyde
CAS No.	1142202-04-7
Molecular Formula	C11H11NO3
Molecular Weight	205.21 g/mol
Synonyms	1-(1,2-Dihydroxyethyl)-1H-indole-3-carboxaldehyde; 1H-Indole-3-carboxaldehyde, 1-(1,2-dihydroxyethyl)-; 3-Formyl-1-(1,2-dihydroxyethyl)indole; 1-(1,2-Dihydroxyethyl)indole-3-carbaldehyde; (1H-Indol-3-yl)-[1,2-dihydroxyethyl]methanone (tautomeric form); Indole-3-glyoxal hydrate derivative
EINECS	Contact for details

Quality Control

Our 1-(1,2-Dihydroxyethyl)-1H-Indole-3-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by spectroscopic methods (NMR, IR), to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.