Description

n-[4-(2-Bromoacetyl)-3-Fluorophenyl]Acetamide is a high-purity fluorinated and brominated aromatic acetamide derivative, serving as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis. Its molecular structure, featuring both a reactive bromoacetyl group and a fluorine substituent, makes it invaluable for constructing complex molecules with specific pharmacological or material properties. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging the fluorine atom for enhanced bioactivity and stability.
• Organic Synthesis Reagent: Serves as a versatile electrophile in cross-coupling reactions, nucleophilic substitutions, and as a precursor for heterocyclic compound synthesis.
• Material Science: Potential monomer or additive in the creation of specialty polymers and advanced materials with unique electronic or surface properties.
• Chemical Biology Probe: Utilized in medicinal chemistry for target identification and validation due to its reactive handle for bioconjugation.

Basic Information

Product Name	n-[4-(2-Bromoacetyl)-3-Fluorophenyl]Acetamide
CAS No.	1141886-90-9
Molecular Formula	C10H9BrFNO2
Molecular Weight	274.09 g/mol
Synonyms	1-(4-Acetamido-2-fluorophenyl)-2-bromoethan-1-one; 2-Bromo-1-(4-acetamido-2-fluorophenyl)ethanone; 4'-Acetamido-2'-fluoro-2-bromoacetophenone; N-(4-(2-Bromoacetyl)-3-fluorophenyl)acetamide; 2-Bromo-1-(2-fluoro-4-acetamidophenyl)ethanone; Acetamide, N-[4-(2-bromoacetyl)-3-fluorophenyl]-
EINECS	Contact for details

Quality Control

Our n-[4-(2-Bromoacetyl)-3-Fluorophenyl]Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.