Description

3-(4-Methylpiperazin-1-Yl)Phenylboronic Acid is a high-value boronic acid derivative featuring a substituted piperazine ring, making it a versatile building block in modern synthetic chemistry. Its primary commercial value lies in its role as a key intermediate in the synthesis of complex pharmaceutical compounds, particularly through Suzuki-Miyaura cross-coupling reactions. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid coupling partner for forming carbon-carbon bonds between aromatic rings, a cornerstone reaction in medicinal chemistry.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require complex aromatic heterocycles.
• Material Science: Potential building block for creating organic electronic materials, such as those used in OLEDs or conductive polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	3-(4-Methylpiperazin-1-Yl)Phenylboronic Acid
CAS No.	1139717-76-2
Molecular Formula	C11H17BN2O2
Molecular Weight	220.08 g/mol
Synonyms	[3-(4-Methyl-1-piperazinyl)phenyl]boronic acid; 3-(4-Methylpiperazin-1-yl)benzeneboronic acid; 3-(N-Methylpiperazino)phenylboronic Acid; 3-(4-Methylpiperazino)phenylboronic Acid; 1-Methyl-4-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]piperazine (Pinacol ester precursor); B-[3-(4-Methyl-1-piperazinyl)phenyl]boronic acid
EINECS	Contact for details

Quality Control

Our 3-(4-Methylpiperazin-1-Yl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.