Description

Benzene, 1-Bromo-2-Fluoro-4-Phenoxy- is a high-purity, multi-functional halogenated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, which combines bromo, fluoro, and phenoxy substituents on a benzene ring, enabling precise structural modifications in target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of complex drug candidates, particularly those requiring halogenated aromatic cores for bioactivity or metabolic stability.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, where the phenoxy and halogen groups contribute to target specificity and efficacy.
• Liquid Crystal & OLED Material Research: Acts as a key building block for creating novel organic electronic materials due to its ability to influence molecular polarity and packing.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to form complex biaryl structures.
• Functional Polymer Monomer: Employed in the synthesis of specialty polymers with tailored properties such as thermal stability, refractive index, or chemical resistance.
• Chemical Research & Development: A versatile reagent for exploring new synthetic methodologies and constructing molecular libraries for screening in various chemical industries.

Basic Information

Product Name	Benzene, 1-Bromo-2-Fluoro-4-Phenoxy-
CAS No.	1138557-58-0
Molecular Formula	C12H8BrFO
Molecular Weight	267.10 g/mol
Synonyms	1-Bromo-2-fluoro-4-phenoxybenzene; 2-Fluoro-4-phenoxybromobenzene; 4-Phenoxy-2-fluorobromobenzene; (2-Fluoro-4-phenoxyphenyl)bromide; 1-Bromo-2-fluoro-4-phenoxybenzene; Benzene, bromofluoro phenoxy derivative; Bromofluorophenoxybenzene
EINECS	Contact for details

Quality Control

Our Benzene, 1-Bromo-2-Fluoro-4-Phenoxy- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.