Description

2-(1,1-Difluoroethyl)-1,3,4-Trifluorobenzene is a high-value, multi-fluorinated aromatic building block of significant interest in advanced chemical synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where the introduction of fluorine atoms is crucial for modulating biological activity, metabolic stability, and lipophilicity. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty materials industries seeking to incorporate complex fluorinated motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel fluorinated drug candidates, particularly in oncology, CNS, and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides where fluorine substitution enhances efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic cores used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Polymer & Specialty Chemicals: Employed in the creation of fluorinated monomers and polymers for high-performance materials with unique chemical resistance and thermal stability.
• Chemical Research & Development: A valuable reagent for exploring new fluorination methodologies and constructing complex molecular architectures in academic and industrial labs.

Basic Information

Product Name	2-(1,1-Difluoroethyl)-1,3,4-Trifluorobenzene
CAS No.	1138445-26-7
Molecular Formula	C8H5F5
Molecular Weight	196.12 g/mol
Synonyms	1,3,4-Trifluoro-2-(1,1-difluoroethyl)benzene; 2-(1,1-Difluoroethyl)-1,3,4-trifluorobenzene; 1-(1,1-Difluoroethyl)-2,4,5-trifluorobenzene; Benzene, 2-(1,1-difluoroethyl)-1,3,4-trifluoro-; α,α-Difluoro-2,4,5-trifluoroethylbenzene
EINECS	Contact for details

Quality Control

Our 2-(1,1-Difluoroethyl)-1,3,4-Trifluorobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Purity (HPLC)	≥ 96.5%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.