Description

1-(1,1-Difluoroethyl)-3-Fluorobenzene is a specialized fluorinated aromatic building block of significant interest in advanced organic synthesis. Its value lies in the unique reactivity imparted by the difluoroethyl and fluorine substituents, enabling precise molecular modifications. This compound is primarily needed by research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for introducing fluorinated motifs into drug candidates to modulate metabolism, bioavailability, and binding affinity.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where fluorine atoms enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for developing specialty polymers and liquid crystals with tailored electronic and surface properties.
• Organic Light-Emitting Diode (OLED) Materials: Investigated as a building block for electron-transport or host materials in display technologies.
• Fluorine Chemistry Research: A valuable substrate for studying novel fluorination reactions and reaction mechanisms in academic and industrial R&D settings.
• Positron Emission Tomography (PET) Tracer Development: Potential use as a precursor for synthesizing fluorine-18 labeled radiopharmaceuticals for medical imaging.

Basic Information

Product Name	1-(1,1-Difluoroethyl)-3-Fluorobenzene
CAS No.	1138445-15-4
Molecular Formula	C8H7F3
Molecular Weight	160.14 g/mol
Synonyms	3-Fluoro-α,α-difluoroethylbenzene; 1-(3-Fluorophenyl)-1,1-difluoroethane; m-Fluoro-α,α-difluoroethylbenzene; 1,1-Difluoro-1-(3-fluorophenyl)ethane; (3-Fluorophenyl)difluoroethane; Difluoro(3-fluorophenyl)ethane; Benzene, 1-(1,1-difluoroethyl)-3-fluoro-
EINECS	Contact for details

Quality Control

Our 1-(1,1-Difluoroethyl)-3-Fluorobenzene is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.