Description

1-Chloro-4-(1,1-Difluoroethyl)-2-(Trifluoromethyl)Benzene is a high-value, multi-fluorinated aromatic building block of significant interest in advanced chemical synthesis. This compound matters for its unique structure, which combines chloro, difluoroethyl, and trifluoromethyl substituents to impart specific electronic and steric properties critical for modifying molecular interactions. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing lipophilic and metabolically stable fluorinated motifs.
• Agrochemical Synthesis: Used in the design and production of advanced pesticides and herbicides, where the fluorinated groups can enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, or organic electronic materials with tailored properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic substitutions, and other transformations to construct complex, fluorinated aromatic systems.
• Life Science Reagents: Potential use in the synthesis of probes, tags, or other reagents for biochemical and diagnostic applications.

Basic Information

Product Name	1-Chloro-4-(1,1-Difluoroethyl)-2-(Trifluoromethyl)Benzene
CAS No.	1138444-94-6
Molecular Formula	C9H6ClF5
Molecular Weight	244.59 g/mol
Synonyms	4-Chloro-α,α-difluoro-α-(trifluoromethyl)toluene; 1-Chloro-4-(1,1-difluoroethyl)-2-(trifluoromethyl)benzene; Benzene, 1-chloro-4-(1,1-difluoroethyl)-2-(trifluoromethyl)-; 2-(Trifluoromethyl)-1-chloro-4-(1,1-difluoroethyl)benzene
EINECS	Contact for details

Quality Control

Our 1-Chloro-4-(1,1-Difluoroethyl)-2-(Trifluoromethyl)Benzene is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.