Description

4-Chloro-2-Formylphenylboronic Acid, Pinacol Ester is a high-value, multifunctional boronic ester building block designed for advanced organic synthesis. This compound is critical for facilitating efficient cross-coupling reactions, particularly the Suzuki-Miyaura coupling, due to its enhanced stability and reactivity profile compared to its free boronic acid counterpart. It is an essential intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially those containing biaryl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides requiring specific chlorinated aromatic structures.
• Material Science Research: Serves as a precursor for creating novel organic electronic materials, ligands for catalysts, and functionalized polymers.
• Suzuki-Miyaura Cross-Coupling: The pinacol ester group offers improved handling and stability, making this reagent highly effective for forming carbon-carbon bonds under mild conditions.
• Chemical Biology Probes: Utilized in the development of sensor molecules and probes where the formyl group allows for further conjugation.
• Liquid Crystal & OLED Materials: Acts as a synthetic intermediate for creating specialized aromatic cores used in display and lighting technologies.

Basic Information

Product Name	4-Chloro-2-Formylphenylboronic Acid, Pinacol Ester
CAS No.	1132669-91-0
Molecular Formula	C₁₃H₁₆BClO₃
Molecular Weight	266.53 g/mol
Synonyms	2-Formyl-4-chlorophenylboronic acid pinacol ester; (4-Chloro-2-formylphenyl)boronic acid pinacol ester; 4-Chloro-2-formylbenzeneboronic acid pinacol ester; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-chlorobenzaldehyde; 5-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde; Pinacol (4-chloro-2-formylphenyl)boronate
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro-2-Formylphenylboronic Acid, Pinacol Ester is produced under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency suitable for research and scale-up applications. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for all shipments upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.