Description

(E)-Ethyl 3-(2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Acrylate is a high-value boronic ester derivative, specifically designed as a key synthetic intermediate in advanced organic transformations. Its core value lies in enabling precise carbon-carbon bond formation, which is fundamental for constructing complex molecular architectures. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-purity building blocks for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs) via Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific aryl-boronate functionalities.
• Material Science Research: Serves as a monomer or precursor for creating advanced organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology Probes: Employed in the development of bioconjugation reagents and molecular probes for diagnostic and research applications.
• Academic & Industrial R&D: A versatile reagent for methodology development and exploring new catalytic cycles in organic chemistry laboratories worldwide.
• Custom Synthesis & Contract Manufacturing: A starting material for the bespoke production of complex, boronate-containing target molecules.

Basic Information

Product Name	(E)-Ethyl 3-(2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Acrylate
CAS No.	1132669-74-9
Molecular Formula	C₁₉H₂₇BO₄
Molecular Weight	330.23 g/mol
Synonyms	Ethyl (E)-3-[2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acrylate; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)cinnamic acid ethyl ester; (E)-Ethyl 3-(2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propenoate; 1132669-74-9; Ethyl 3-(2-(Pinacolboryl)phenyl)acrylate; trans-Ethyl 3-(2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acrylate; Pinacol (E)-3-Ethoxycarbonylvinylphenylboronate
EINECS	Contact for details

Quality Control

Our (E)-Ethyl 3-(2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Acrylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your quality assurance protocols. We adhere to cGMP principles where applicable to ensure supply chain reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal purity and reactivity. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.