Description

Tetrahydropyran-4-Boronic Acid Pinacol Ester is a high-purity, heterocyclic boronic ester building block essential for modern synthetic chemistry. This compound matters as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex molecules for advanced research and development. It is primarily needed by pharmaceutical, agrochemical, and material science industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing drug candidates containing the tetrahydropyran moiety, particularly in medicinal chemistry for CNS and antiviral research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides through palladium-catalyzed cross-coupling methodologies.
• Material Science & OLED Development: Serves as a precursor for creating advanced organic electronic materials, including charge-transport layers and emissive materials in OLED devices.
• Ligand & Catalyst Preparation: Employed in the synthesis of sophisticated ligands for asymmetric catalysis and organometallic complexes.
• Chemical Biology & Probe Development: Utilized for creating bioconjugates and molecular probes for studying biological processes and target engagement.
• Polymer Chemistry: Acts as a monomer or functionalization agent in the synthesis of specialty polymers with tailored properties.

Basic Information

Product Name	Tetrahydropyran-4-Boronic Acid Pinacol Ester
CAS No.	1131912-76-9
Molecular Formula	C11H21BO3
Molecular Weight	212.10 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)tetrahydropyran; Tetrahydropyran-4-ylboronic Acid Pinacol Ester; THP-4-Boronic Acid Pinacol Ester; 4-(Pinacolatoboryl)tetrahydropyran; 4-Tetrahydropyranboronic Acid Pinacol Ester; 2-(Oxan-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our Tetrahydropyran-4-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (argon or nitrogen) to prevent moisture absorption and decomposition. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.