Description

4,4,5,5-Tetramethyl-2-(1,2,3,4-tetrahydronaphthalen-2-yl)-1,3,2-dioxaborolane is a specialized organoboron reagent, specifically a pinacol boronic ester, valued for its stability and versatility in advanced synthetic chemistry. Its core value proposition lies in serving as a crucial coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex carbon-carbon bonds. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for drug discovery and fine chemical synthesis.

Application

• Key intermediate in the synthesis of active pharmaceutical ingredients (APIs) via Suzuki-Miyaura cross-coupling reactions.
• Building block for creating novel organic electronic materials and liquid crystals.
• Precursor in the development of agrochemicals and specialty fine chemicals.
• Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Reagent in polymer chemistry for incorporating functional aromatic units.
• Valuable tool in academic and industrial R&D for exploring new catalytic methodologies.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-(1,2,3,4-tetrahydronaphthalen-2-yl)-1,3,2-dioxaborolane
CAS No.	1130490-92-4
Molecular Formula	C₁₈H₂₅BO₂
Molecular Weight	284.20 g/mol
Synonyms	2-(1,2,3,4-Tetrahydronaphthalen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-(1,2,3,4-Tetrahydronaphthalen-2-yl)-1,3,2-dioxaborolane, 4,4,5,5-tetramethyl-; 2-Tetralinyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 1,2,3,4-Tetrahydronaphthalen-2-ylboronic acid pinacol ester; 5,6,7,8-Tetrahydronaphthalen-2-ylboronic acid pinacol ester; Tetralin-2-ylboronic acid pinacol ester; Pinacol (1,2,3,4-tetrahydronaphthalen-2-yl)boronate
EINECS	Contact for details

Quality Control

Our production of 4,4,5,5-Tetramethyl-2-(1,2,3,4-tetrahydronaphthalen-2-yl)-1,3,2-dioxaborolane adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All materials are supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, generated using validated analytical methods such as NMR, HPLC, and GC. We are committed to meeting the exacting standards required for research and cGMP manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.