Description

2,4-Dimethyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-Benzenamine is a high-purity, advanced pharmaceutical intermediate featuring a protected boronic acid ester group. This compound is a critical building block in modern synthetic chemistry, enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, especially those requiring specific aryl-aryl linkages.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides with tailored properties.
• Material Science Research: Serves as a monomer or functional unit in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Cross-Coupling Reactions: A versatile reagent for Suzuki-Miyaura coupling, a cornerstone reaction for constructing biaryl structures in fine chemical synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for target identification and validation.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing specialized ligands used in homogeneous catalysis.

Basic Information

Product Name	2,4-Dimethyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-Benzenamine
CAS No.	1126367-54-1
Molecular Formula	C14H22BNO2
Molecular Weight	247.14 g/mol
Synonyms	5-Amino-2,4-dimethylphenylboronic acid pinacol ester; 2,4-Dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline; (5-Amino-2,4-dimethylphenyl)boronic acid pinacol ester; Benzenamine, 2,4-dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 2,4-Dimethyl-5-(pinacolatoboryl)aniline; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,4-dimethylbenzenamine
EINECS	Contact for details

Quality Control

Our 2,4-Dimethyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-Benzenamine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for research and commercial-scale synthesis. Each lot is analyzed using advanced techniques including HPLC, NMR, and GC-MS. Certificates of Analysis (COA) detailing purity and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.