Description

4-Acetyl-n-{2-Oxo-2-[(2,2,2-Trifluoroethyl)Amino]Ethyl}-1-Naphthamide is a high-purity, advanced pharmaceutical intermediate characterized by its unique naphthalene and trifluoroethyl amide structure. This compound matters for its critical role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in research areas targeting specific biological pathways. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the research and development of new drug candidates, especially for targeted therapies.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides requiring fluorinated components for enhanced activity and stability.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Fluorinated Compound Production: Essential for introducing the trifluoroethylamino moiety into complex molecules to alter their physicochemical properties.
• Peptidomimetic Development: Utilized in the design of peptide-like molecules that mimic natural peptides for therapeutic applications.
• Material Science Research: Potential precursor for specialty polymers or organic electronic materials due to its fused aromatic system.

Basic Information

Product Name	4-Acetyl-n-{2-Oxo-2-[(2,2,2-Trifluoroethyl)Amino]Ethyl}-1-Naphthamide
CAS No.	1125812-54-5
Molecular Formula	C₁₇H₁₅F₃N₂O₃
Molecular Weight	352.31 g/mol
Synonyms	4-Acetyl-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]-1-naphthamide; 1-Naphthalenecarboxamide, 4-acetyl-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]-; N-(2-Oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)-4-acetyl-1-naphthamide; 4-Acetyl-N-(2-oxo-2-(2,2,2-trifluoroethylamino)ethyl)naphthalene-1-carboxamide; 1125812-54-5; TFEAEAN; 4-Acetyl-1-naphthamide TFEA derivative
EINECS	Contact for details

Quality Control

Our 4-Acetyl-n-{2-Oxo-2-[(2,2,2-Trifluoroethyl)Amino]Ethyl}-1-Naphthamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under anhydrous conditions when possible. Keep away from strong acids/bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.