Description

1-(3-Bromo-5-(tert-Butyl)Phenyl)Ethanone is a high-purity brominated aromatic ketone building block of significant importance in advanced organic synthesis. This compound serves as a critical intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is essential for research institutions and industrial manufacturers engaged in fine chemical production, where precise functionalization and reliable quality are paramount.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, leveraging the tert-butyl and bromo substituents for enhanced bioactivity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and advanced polymers requiring specific bromo-aryl functionalities.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up production under cGMP conditions for clinical trial materials.

Basic Information

Product Name	1-(3-Bromo-5-(tert-Butyl)Phenyl)Ethanone
CAS No.	1124138-68-6
Molecular Formula	C₁₂H₁₅BrO
Molecular Weight	255.15 g/mol
Synonyms	3'-Bromo-5'-tert-butylacetophenone; 1-(3-Bromo-5-tert-butylphenyl)ethan-1-one; 3-Bromo-5-(tert-butyl)acetophenone; 1-Acetyl-3-bromo-5-tert-butylbenzene; 3'-Bromo-5'-(1,1-dimethylethyl)acetophenone; 3-Bromo-5-tert-butylphenyl methyl ketone; Ethanone, 1-[3-bromo-5-(1,1-dimethylethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our 1-(3-Bromo-5-(tert-Butyl)Phenyl)Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring cGMP compliance for pharmaceutical development and other regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and should be kept under inert atmosphere if long-term storage is required to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.