Description

8-Benzyl-2,8-Diazaspiro[4.5]Decan-1-One is a high-purity, advanced pharmaceutical intermediate belonging to the diazaspiro decane class of heterocyclic compounds. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily utilized by pharmaceutical R&D departments, fine chemical manufacturers, and contract research organizations (CROs) engaged in modern drug discovery programs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates targeting neurological disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in high-throughput screening for new therapeutic agents.
• API Development: Used in the process development and scale-up of potential Active Pharmaceutical Ingredients, especially those with spirocyclic architectures.
• CNS Drug Discovery: A key structural component in the research of novel treatments for conditions such as depression, anxiety, and schizophrenia.
• Oncological Research: Employed in the synthesis of experimental molecules designed to modulate specific biological pathways involved in cancer.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP guidelines.

Basic Information

Product Name	8-Benzyl-2,8-Diazaspiro[4.5]Decan-1-One
CAS No.	1123242-53-4
Molecular Formula	C15H20N2O
Molecular Weight	244.33 g/mol
Synonyms	8-Benzyl-2,8-diazaspiro[4.5]decan-1-one; 1-Oxo-8-benzyl-2,8-diazaspiro[4.5]decane; 2,8-Diazaspiro[4.5]decan-1-one, 8-benzyl-; 8-Benzyl-1-oxo-2,8-diazaspiro[4.5]decane; Benzyl-diazaspirodecanoine; BDD; CAS 1123242-53-4
EINECS	Contact for details

Quality Control

Our 8-Benzyl-2,8-Diazaspiro[4.5]Decan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can adhere to cGMP standards for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.