Description

6-Trifluoromethyl-Chroman-4-One is a high-purity fluorinated organic building block of significant interest in advanced chemical synthesis. Its core value lies in the trifluoromethyl group, which is a key structural motif for modulating the physicochemical and biological properties of target molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disease research.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the CF3 group enhances lipophilicity and metabolic stability.
• Material Science Precursor: Serves as a specialty monomer or additive in the development of advanced polymers with unique optical or surface properties.
• Fluorine Chemistry Research: An important substrate for studying fluorination reactions and the behavior of fluorinated heterocycles in synthetic pathways.
• Ligand and Catalyst Development: Utilized in the design of novel chiral ligands or organocatalysts for asymmetric synthesis.

Basic Information

Product Name	6-Trifluoromethyl-Chroman-4-One
CAS No.	1122410-37-0
Molecular Formula	C10H7F3O2
Molecular Weight	216.16 g/mol
Synonyms	6-(Trifluoromethyl)-4-chromanone; 4H-1-Benzopyran-4-one, 6-(trifluoromethyl)-; 6-Trifluoromethylchroman-4-one; 6-(Trifluoromethyl)-2,3-dihydro-4H-chromen-4-one; 6-Trifluoromethyl-4-chromanone; Chroman-4-one, 6-trifluoromethyl-
EINECS	Contact for details

Quality Control

Our 6-Trifluoromethyl-Chroman-4-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.