Description

Dioxaborolan-2-Yl)Pyridine Hydrochloride is a high-value organoboron building block, specifically a pyridine-substituted pinacol boronic ester in its hydrochloride salt form. This compound is essential for facilitating efficient cross-coupling reactions, particularly Suzuki-Miyaura couplings, due to its enhanced stability and reactivity profile compared to boronic acids. It is a critical intermediate for researchers and manufacturers in the pharmaceutical and advanced materials sectors developing novel active pharmaceutical ingredients (APIs), agrochemicals, and organic electronic materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially those containing biaryl or heterobiaryl motifs via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and production of modern pesticides and herbicides that require specific pyridine-boron containing structures for enhanced efficacy.
• Material Science Research: Serves as a precursor for creating organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs) with tailored electronic and structural properties.
• Chemical Biology & Probe Development: Employed in the design and synthesis of molecular probes and sensors for bioimaging and diagnostic applications.
• Catalyst Ligand Preparation: Utilized as a starting material for synthesizing novel nitrogen-boron containing ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences industry.

Basic Information

Product Name	Dioxaborolan-2-Yl)Pyridine Hydrochloride
CAS No.	1121057-75-7
Molecular Formula	C11H15BClNO2
Molecular Weight	239.51 g/mol
Synonyms	2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine hydrochloride; Pyridine-2-boronic acid pinacol ester hydrochloride; 2-Pyridinylboronic acid, pinacol ester, hydrochloride; 2-(Pinacolatoboryl)pyridine hydrochloride; 2-Pyridylboronic Acid Pinacol Ester Hydrochloride; 2-Pyridineboronic Acid Pinacol Ester Hydrochloride; 2-PyridylBPin Hydrochloride
EINECS	Contact for details

Quality Control

Our Dioxaborolan-2-Yl)Pyridine Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, meeting the stringent requirements of research and cGMP-grade production. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant quality management standards to guarantee supply reliability and traceability for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (NMR)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.