Description

[({5-[(Cyclopropylamino)Carbonyl]-1,2,4-Oxadiazol-3-Yl}Methyl)Thio]Acetic Acid CAS NO 1119452-73-1 is a high-purity, advanced pharmaceutical intermediate featuring a unique oxadiazole-thioacetic acid hybrid structure. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel bioactive molecules targeting various therapeutic areas. It is primarily sought after by pharmaceutical R&D laboratories, agrochemical innovators, and fine chemical manufacturers for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, especially those requiring the oxadiazole pharmacophore for biological activity.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new therapeutic agents.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides, fungicides, or insecticides with specific modes of action.
• Bioconjugation & Chemical Biology: The thioacetic acid moiety can be utilized for conjugation reactions, linking the oxadiazole core to other molecules, peptides, or surfaces for probe development.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	[({5-[(Cyclopropylamino)Carbonyl]-1,2,4-Oxadiazol-3-Yl}Methyl)Thio]Acetic Acid
CAS No.	1119452-73-1
Molecular Formula	C10H13N3O4S
Molecular Weight	271.29 g/mol
Synonyms	2-[[[5-[(Cyclopropylamino)carbonyl]-1,2,4-oxadiazol-3-yl]methyl]thio]acetic acid; ({5-[(Cyclopropylcarbamoyl)]-1,2,4-oxadiazol-3-yl}methylsulfanyl)acetic acid; 3-[(Carboxymethyl)thiomethyl]-5-(cyclopropylaminocarbonyl)-1,2,4-oxadiazole; 5-(Cyclopropylcarbamoyl)-1,2,4-oxadiazole-3-methanethioacetic acid; CPOCA intermediate; Oxadiazole-thioacetic acid derivative
EINECS	Contact for details

Quality Control

Our [({5-[(Cyclopropylamino)Carbonyl]-1,2,4-Oxadiazol-3-Yl}Methyl)Thio]Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and stored in the original packaging until use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.