Description

2-Methyl-5-[3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]-1,3,4-Oxadiazole is a high-value, multi-functional organic building block that combines an oxadiazole heterocycle with a pinacol boronate ester group. This unique structure makes it a critical intermediate for Suzuki-Miyaura cross-coupling reactions, enabling the efficient synthesis of complex molecules. It is essential for researchers and manufacturers in pharmaceutical development, agrochemical research, and advanced materials science who require precise and reliable synthetic pathways.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of novel heterocyclic compounds with potential therapeutic activity.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the oxadiazole moiety can contribute to biological activity.
• Material Science & OLED Development: Serves as a precursor for creating organic electronic materials, including electron-transport layers and emitters for organic light-emitting diodes (OLEDs).
• Ligand & Catalyst Development: Employed in the design and synthesis of novel ligands and organometallic catalysts for various transition metal-catalyzed processes.
• Polymer Chemistry: Can be incorporated into polymer backbones to create functional materials with specific electronic or mechanical properties.
• Chemical Biology & Probe Synthesis: Useful for creating molecular probes and bioconjugates due to the reactivity of the boronate ester group under mild conditions.

Basic Information

Product Name	2-Methyl-5-[3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]-1,3,4-Oxadiazole
CAS No.	1119090-20-8
Molecular Formula	C₁₅H₁₉BN₂O₃
Molecular Weight	286.14 g/mol
Synonyms	2-Methyl-5-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-1,3,4-oxadiazole; 3-(5-Methyl-1,3,4-oxadiazol-2-yl)phenylboronic acid pinacol ester; 2-Methyl-5-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1,3,4-oxadiazole; 1119090-20-8; (3-(5-Methyl-1,3,4-oxadiazol-2-yl)phenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Every batch of 2-Methyl-5-[3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]-1,3,4-Oxadiazole is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.