Description

3-Methoxy-2-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzonitrile is a high-value boronic ester derivative, a crucial building block in modern synthetic organic chemistry. Its core value lies in enabling efficient cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Ligand and Catalyst Development: Serves as a starting material for creating sophisticated ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs and semiconductors.
• Chemical Biology Probes: Utilized to build bioconjugates and molecular probes for studying biological processes and target identification.
• Custom Synthesis and Contract Manufacturing: A critical reagent for custom synthesis houses and CROs/CMOs serving the global life sciences industry.

Basic Information

Item	Details
Product Name	3-Methoxy-2-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzonitrile
CAS No.	1116096-84-4
Molecular Formula	C14H18BNO3
Molecular Weight	259.11 g/mol
Synonyms	2-Cyano-6-methoxyphenylboronic acid pinacol ester; (2-Cyano-6-methoxyphenyl)boronic acid pinacol ester; 2-Methoxy-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile; 6-Methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile; Benzonitrile, 3-methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; Pinacol (2-cyano-6-methoxyphenyl)boronate
EINECS	Contact for details

Quality Control

Every batch of 3-Methoxy-2-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzonitrile undergoes rigorous analytical testing to ensure it meets the stringent purity requirements for advanced synthetic applications. Our quality assurance protocols are designed to guarantee batch-to-batch consistency and reliability. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.